Alex J. Vanni, MD | Lahey Hospital and Medical Center, Burlington, MA (781) 744-8762

Urethral stricture disease is a condition in which scar tissue narrows the urethra, restricting urinary flow and leading to symptoms that can significantly affect quality of life. While some strictures can be managed temporarily, many require specialized reconstructive surgery for durable, long-term relief.

Dr. Alex J. Vanni is a nationally recognized leader in the treatment of urethral stricture disease, with patients referred from across the United States for evaluation and surgical management of complex and recurrent cases.

Urethral Stricture Educational Video

What Is Urethral Stricture Disease?

A urethral stricture occurs when fibrosis or scarring develops within the urethra, causing narrowing that obstructs urine flow. Strictures may develop due to:

Left untreated or inadequately treated, strictures often progress or recur, leading to worsening symptoms and repeated procedures.

Symptoms of a Urethral Stricture

Common symptoms include:

Patients with long-standing or recurrent symptoms often benefit from evaluation at a high-volume reconstructive urology center.

Urethral Stricture Disease Guide - Diagnosis, Treatment Pathways, and Success Rates

How Is Urethral Stricture Disease Treated?

Treatment depends on the length, location, cause, and prior treatments of the stricture.

Non-Definitive Treatments

  • Urethral dilation
  • Optilume Dilation — Watch Video
  • Direct vision internal urethrotomy (DVIU)

While these approaches may provide short-term relief, they are associated with high recurrence rates, particularly for longer or recurrent strictures when compared to urethroplasty.

Definitive Surgical Treatment: Urethroplasty

Urethroplasty is the gold-standard treatment for most urethral strictures and offers the highest chance of long-term cure.

Dr. Vanni specializes in advanced urethroplasty techniques, including:

  • Excision and primary anastomosis
  • Buccal mucosa graft urethroplasty
  • Staged reconstruction for complex or lichen sclerosus-associated disease
  • Reconstruction for recurrent and failed prior repairs

Why See a High-Volume Urethral Reconstruction Specialist?

Outcomes after urethral stricture surgery are highly dependent on surgeon experience and case volume. Surgeons who perform particular procedures frequently tend to have better technical skill, superior outcomes, and fewer complications.

Having performed over 2,000 urethral reconstructions, Dr. Vanni is a high-volume reconstructive urologist who leads one of the nation's busiest practices dedicated to urethral stricture surgery, and the busiest reconstructive urology program in New England. His practice focuses almost exclusively on complex urethral and genitourinary reconstruction, with outcomes that reflect meticulous surgical technique, thoughtful patient selection, and long-term durability.

Patients and referring physicians seek his expertise for:

National Referral Center for Urethral Stricture Disease

Patients are referred nationally to Dr. Vanni for expert evaluation and management of urethral stricture disease. He works closely with referring urologists to provide comprehensive consultation, definitive surgical care, and coordinated long-term follow-up.

Dr. Vanni's approach to urethral reconstruction is guided by evidence-based surgical guidelines and informed by peer-reviewed research published in leading urology journals.

Treatment Outcomes at a Glance

Success Rate

95% success rate for most urethral strictures

Surgery Duration

Outpatient surgery typically taking 1–3 hours depending on complexity

Recovery

Return to full activity once catheter is removed, typically 1–3 weeks

20+ Years Experience in Reconstructive Urology Certified by the American Board of Urology American Urological Association Member Society of Genitourinary Reconstructive Surgeons Fellow of the American College of Surgeons

Schedule a Consultation

If you have been diagnosed with urethral stricture disease—or have persistent urinary symptoms after prior treatment—expert evaluation can help determine the most effective and durable treatment options.

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