Alex J. Vanni, MD | Lahey Clinic, Burlington MA(781) 744-8762

Peyronie's Disease: Curvature and Treatment Choices

About this video

Peyronie's disease can cause a curved, and sometimes painful, erection. Dr. Alex Vanni explains what causes the curve, the acute and chronic phases, collagenase (Xiaflex) injections, plication and grafting surgery, and when a penile implant is the best option, so you can weigh the trade-offs and choose the right treatment.

Key points

  • Peyronie's disease affects about 11–13% of men
  • It can cause curvature, an indentation, an hourglass narrowing, or shortening
  • The acute phase lasts 6–18 months; surgery is considered once the curve has been stable for 3–6 months
  • Xiaflex is up to 4 cycles (8 injections), with about a 30% average improvement in curvature
  • Plication suits curves under 60–70°; grafting suits larger or complex curves
  • A penile implant with straightening can treat curvature and erectile dysfunction together

Chapters

  1. Introduction
  2. What Peyronie's Disease Is
  3. How It Changes Over Time
  4. Choosing a Treatment
  5. Surgical Options
  6. Your Goals

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Talk with Dr. Vanni

Dr. Alex J. Vanni is a fellowship-trained reconstructive urologic surgeon at the Lahey Clinic in Burlington, Massachusetts, caring for patients from Boston and across New England.

New patients: (781) 744-8762 · Established patients with clinical questions: (781) 744-8420

This video is for general patient education and does not replace advice from your own doctor. Every patient is different; please talk with your care team about your situation. Watch on YouTube.

Dr. Vanni